Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies

Tantawy, SI; Sarkar, A; Hubner, S; Tan, Z; Wierda, WG; Eldeib, A; Zhang, SX; Kornblau, S; Gandhi, V

Gandhi, V (通讯作者),Univ Texas MD Anderson Canc Ctr, Dept Expt Thera peut, 1901 East Rd, Houston, TX 77230 USA.

CLINICAL CANCER RESEARCH, 2023; 29 (2): 446

Abstract

Purpose: Several MCL-1 inhibitors (MCL-1i), including AMG-176 and AZD5991, have shown promise in preclinical studies and are being tested for the trea......

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