cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+T cell function and anti-tumor immunity

Zhao, YL; Caron, C; Chan, YY; Lee, CK; Xu, XZ; Zhang, JB; Masubuchi, T; Wu, C; Bui, JD; Hui, EF

Zhao, YL; Hui, EF (通讯作者)，Univ Calif San Diego, Sch Biol Sci, Dept Cell & Dev Biol, La Jolla, CA 92093 USA.;Bui, JD (通讯作者)，Univ Calif San Diego, Dept Pathol, La Jolla, CA 92093 USA.

IMMUNITY, 2023; 56 (6): 1187

Abstract

B7 ligands (CD80 and CD86), expressed by professional antigen-presenting cells (APCs), activate the main co-stimulatory receptor CD28 on T cells in tr......

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