Ago2 protects Drosophila siRNAs and microRNAs from target-directed degradation, even in the absence of 2 '-O-methylation

Kingston, ER; Bartel, DP

Bartel, DP (corresponding author), Howard Hughes Med Inst, Cambridge, MA 02142 USA.

RNA, 2021; 27 (6): 710

Abstract

Target-directed microRNA (miRNA) degradation (TDMD), which is mediated by the protein ZSWIM8, plays a widespread role in shaping miRNA abundances acro......

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