Catalytic iron-carbene intermediate revealed in a cytochrome C carbene transferase

Lewis, RD; Garcia-Borras, M; Chalkley, MJ; Buller, AR; Houk, KN; Kan, SBJ; Arnold, FH

Houk, KN (reprint author), Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018; 115 (28): 7308

Abstract

Recently, heme proteins have been discovered and engineered by directed evolution to catalyze chemical transformations that are biochemically unpreced......

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