Thymic Epithelial Cell-Derived IL-15 and IL-15 Receptor alpha Chain Foster Local Environment for Type 1 Innate Like T Cell Development

Tao, HS; Li, L; Liao, NS; Schluns, KS; Luckhart, S; Sleasman, JW; Zhong, XP

Zhong, XP (corresponding author), Duke Univ, Med Ctr, Dept Pediat Allergy & Immunol, Durham, NC 27710 USA.; Zhong, XP (corresponding author), Duke Univ, Med Ctr, Dept Immunol, Durham, NC 27710 USA.; Zhong, XP (corresponding author), Duke Univ, Med Ctr, Duke Canc Inst, Durham, NC 27710 USA.

FRONTIERS IN IMMUNOLOGY, 2021; 12 ():

Abstract

Expression of tissue-restricted antigens (TRAs) in thymic epithelial cells (TECs) ensures negative selection of highly self-reactive T cells to establ......

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