The binding epitope of sintilimab on PD-1 revealed by AbMap

Ma, ML; Qi, H; Hu, CS; Xu, ZW; Wu, FL; Wang, N; Lai, DY; Li, Y; Zhang, HN; Jiang, HW; Meng, QF; Guo, SJ; Kang, YN; Zhao, XD; Li, H; Tao, SC

Li, H (corresponding author), Shanghai Jiao Tong Univ, Sch Biomed Engn, Shanghai 200240, Peoples R China.; Zhao, XD; Tao, SC (corresponding author), Shanghai Jiao Tong Univ, Shanghai Ctr Syst Biomed, Key Lab Syst Biomed, Minist Educ, Shanghai 200240, Peoples R China.; Li, H (corresponding author), Shanghai Jiao Tong Univ, BioID Ctr, Sch Biomed Engn, Shanghai 200240, Peoples R China.; Tao, SC (corresponding author), Shanghai Jiao Tong Univ, State Key Lab Oncogenes, Shanghai 200240, Peoples R Chin

ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021; 53 (5): 628

Abstract

PD-1 plays an important role as an immune checkpoint. Sintilimab is a newly approved PD-1 antibody for cancer immunotherapy with an unknown binding ep......

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