Clinical Pharmacokinetics and Pharmacodynamics of Dabrafenib

Puszkiel, A; Noe, G; Bellesoeur, A; Kramkimel, N; Paludetto, MN; Thomas-Schoemann, A; Vidal, M; Goldwasser, F; Chatelut, E; Blanchet, B

Blanchet, B (reprint author), Univ Paris 05, Sorbonne Paris Cite, CNRS, UMR8638,Fac Pharm,PRES, Paris, France.; Blanchet, B (reprint author), Cochin Univ Hosp, AP HP, Dept Pharmacokinet & Pharmacochem, CERIA,CARPEM, 27 Rue Faubourg St Jacques, F-75014 Par

CLINICAL PHARMACOKINETICS, 2019; 58 (4): 451

Abstract

Dabrafenib is a potent and selective inhibitor of BRAF-mutant kinase that is approved, as monotherapy or in combination with trametinib (mitogen-activ......

Full Text Link