Sensing of mycobacterial arabinogalactan by galectin-9 exacerbates mycobacterial infection

Wu, XY; Wu, Y; Zheng, RJ; Tang, F; Qin, LH; Lai, DT; Zhang, L; Chen, LM; Yan, B; Yang, H; Wang, Y; Li, FF; Zhang, JY; Wang, F; Wang, L; Cao, YJ; Ma, MT; Liu, ZH; Chen, JX; Huang, XC; Wang, J; Jin, RL; Wang, P; Sun, Q; Sha, W; Lyu, LD; Moura-Alves, P; Dorhoi, A; Pei, G; Zhang, P; Chen, JY; Gao, SR; Randow, F; Zeng, GC; Chen, C; Ye, XS; Kaufmann, SHE; Liu, HP; Ge, BX

Liu, HP; Ge, BX (corresponding author), Tongji Univ, Shanghai Pulm Hosp, Shanghai Key Lab TB, Sch Med, Shanghai, Peoples R China.; Ye, XS (corresponding author), Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing, Peoples R China.; Kaufmann, SHE; Liu, HP (corresponding author), Max Planck Inst Infect Biol, Dept Immunol, Berlin, Germany.; Kaufmann, SHE (corresponding author), Texas A&M Univ, Hagler Inst Adv Study, College Stn, TX USA.; Kaufmann, SHE (corresponding author

EMBO REPORTS, 2021; 22 (7):

Abstract

Mycobacterial arabinogalactan (AG) is an essential cell wall component of mycobacteria and a frequent structural and bio-synthetical target for anti-t......

Full Text Link