SECTM1-based CAR T cells enriched with CD7-low/negative subsets exhibit efficacy in CD7-positive malignancies

Wei, WW; Ma, HY; Yang, D; Sun, B; Tang, J; Zhu, YJ; Chen, XC; Huang, XO; Liu, JZ; Hu, ZF; Liu, T; Zou, LQ; Zhao, XD

Zhao, XD (通讯作者)，Sichuan Univ, West China Hosp, 37 Guoxue Alley, Chengdu 610041, Peoples R China.;Zou, LQ (通讯作者)，Sichuan Univ, West China Hosp, Dept Med Oncol, Canc Ctr, 37 Guoxue Alley, Chengdu 610041, Peoples R China.;Liu, T (通讯作者)，Sichuan Univ, Inst Hematol, Dept Hematol, West China Hosp, 37 Guoxue Alley, Chengdu 610041, Peoples R China.

BLOOD ADVANCES, 2023; 7 (13): 2941

Abstract

CD7 has been found to be a promising chimeric antigen receptor (CAR) T cell target in several clinical trials. However, its expression on normal T cel......

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