Nine-Step Stereoselective Synthesis of Islatravir from Deoxyribose

Nawrat, CC; Whittaker, AM; Huffman, MA; McLaughlin, M; Cohen, RD; Andreani, T; Ding, BW; Li, HM; Weisel, M; Tschaen, DM

Nawrat, CC; Whittaker, AM (corresponding author), Merck & Co Inc, Dept Proc Res & Dev, Rahway, NJ 07065 USA.

ORGANIC LETTERS, 2020; 22 (6): 2167

Abstract

A stereoselective nine-step synthesis of the potent HIV nucleoside reverse transcriptase translocation inhibitor (NRTTI) islatravir (EfdA, MK-8591) fr......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索