The Natural Alkaloid (-)-N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex

Feng, L; Shang, RR; Wang, XJ; Li, L; Li, X; Gong, YX; Shi, LY; Wang, JW; Qian, ZY; Tan, NH; Wang, Z

Tan, NH; Wang, Z (通讯作者),China Pharmaceut Univ, Sch Tradit Chinese Pharm, State Key Lab Nat Med, Nanjing 211198, Peoples R China.

JOURNAL OF NATURAL PRODUCTS, 2023; 86 (6): 1449

Abstract

Colorectal cancer (CRC) is an exceptionally deadly disease,whereaseffective therapeutic drugs for CRC have declined over the past fewdecades. Natural ......

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