Structural identification of lysophosphatidylcholines as activating ligands for orphan receptor GPR119

Xu, PY; Huang, SJ; Guo, SM; Yun, Y; Cheng, X; He, XH; Cai, PJ; Lan, Y; Zhou, H; Jiang, HL; Jiang, Y; Xie, X; Xu, HE

Xie, X; Xu, HE (通讯作者)，Chinese Acad Sci, Shanghai Inst Mat Med, CAS Key Lab Receptor Res, Shanghai, Peoples R China.;Xie, X (通讯作者)，Univ Chinese Acad Sci, Sch Pharmaceut Sci & Technol, Hangzhou Inst Adv Study, Hangzhou, Peoples R China.;Xu, HE (通讯作者)，Univ Chinese Acad Sci, Beijing, Peoples R China.;Jiang, Y; Xie, X; Xu, HE (通讯作者)，ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai, Peoples R China.;Jiang, Y (通讯作者)，Lingang Lab, Shanghai, Peoples R China.;Xie, X; Xu, HE (通讯作者)，Chinese Acad Sci, Shan

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2022; 29 (9): 863

Abstract

Lysophosphatidylcholine (LPC) is an essential mediator in human lipid metabolism and is associated with a variety of diseases, but the exact identity ......

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