Phosphorylation of SOCS1 Inhibits the SOCS1-p53 Tumor Suppressor Axis

Saint-Germain, E; Mignacca, L; Huot, G; Acevedo, M; Moineau-Vallee, K; Calabrese, V; Bourdeau, V; Rowell, MC; Ilangumaran, S; Lessard, F; Ferbeyre, G

Lessard, F (reprint author), Univ Montreal, Dept Biochim & Med Mol, Montreal, PQ, Canada.; Ferbeyre, G (reprint author), Univ Montreal, 2900 Edouard Montpetit, Montreal, PQ H3C 3J7, Canada.

CANCER RESEARCH, 2019; 79 (13): 3306

Abstract

Expression of the suppressor of cytokine signaling-1 (SOCS1) is inactivated in hematopoietic and solid cancers by promoter methylation, miRNA-mediated......

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