An improved synthesis of adefovir and related analogues

Jones, DJ; O'Leary, EM; O'Sullivan, TP

O'Sullivan, TP (reprint author), Univ Coll Cork, Sch Chem, Cork, Ireland.; O'Sullivan, TP (reprint author), Univ Coll Cork, Analyt & Biol Chem Res Facil, Cork, Ireland.; O'Sullivan, TP (reprint author), Univ Coll Cork, Sch Pharm, Cork, Ireland.

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2019; 15 (): 801

Abstract

An improved synthesis of the antiviral drug adefovir is presented. Problems associated with current routes to adefovir include capricious yields and a......

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