Anti-neoplastic phramacophore benzophenone-1 coumarin (BP-1C) targets JAK2 to induce apoptosis in lung cancer

Sherapura, A; Malojirao, VH; Thirusangu, P; Sharath, BS; Kandagalla, S; Vigneshwaran, V; Novak, J; Ranganatha, L; Ramachandra, YL; Baliga, SM; Khanum, SA; Prabhakar, BT

Prabhakar, BT (通讯作者),Kuvempu Univ, Sahyadri Sci Coll, Postgrad Dept Studies & Res Biotechnol, Mol Biomed Lab, Shivamogga 577203, Karnataka, India.;Khanum, SA (通讯作者),Univ Mysore, Yuvarajas Coll Autonomous, Dept Chem, Mysuru 570005, Karnataka, India.

APOPTOSIS, 2022; 27 (1-2): 49

Abstract

Reigning of the abnormal gene activation associated with survival signalling in lung cancer leads to the anomalous growth and therapeutic failure. Tar......

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