Competition of calcified calmodulin N lobe and PIP2 to an LQT mutation site in Kv7.1 channel

Tobelaim, WS; Dvir, M; Lebel, G; Cui, M; Buki, T; Peretz, A; Marom, M; Haitin, Y; Logothetis, DE; Hirsch, JA; Attali, B

Attali, B (reprint author), Tel Aviv Univ, Sackler Fac Med, Dept Physiol & Pharmacol, IL-69978 Tel Aviv, Israel.; Attali, B (reprint author), Tel Aviv Univ, Sagol Sch Neurosci, IL-69978 Tel Aviv, Israel.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017; 114 (5): E869

Abstract

Voltage-gated potassium 7.1 (Kv7.1) channel and KCNE1 protein coassembly forms the slow potassium current I-KS that repolarizes the cardiac action pot......

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