Predicting the Mitochondrial Toxicity of Small Molecules: Insights from Mechanistic Assays and Cell Painting Data

de Lomana, MG; Zapata, PAM; Montanari, F

de Lomana, MG (通讯作者),Bayer AG, Machine Learning Res Res & Dev, Pharmaceut, D-13353 Berlin, Germany.

CHEMICAL RESEARCH IN TOXICOLOGY, 2023; 36 (7): 1107

Abstract

Mitochondrial toxicityis a significant concern in the drug discoveryprocess, as compounds that disrupt the function of these organellescan lead to ser......

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