Acetylation Targeting Chimera Enables Acetylation of the Tumor Suppressor p53

Kabir, M; Sun, N; Hu, XP; Martin, TC; Yi, JJ; Zhong, Y; Xiong, Y; Kaniskan, HÜ; Gu, W; Parsons, R; Jin, J

Jin, J (通讯作者)，Mt Sinai Ctr Therapeut Discovery, Icahn Sch Med Mt Sinai, Dept Pharmacol Sci, New York, NY 10029 USA.;Jin, J (通讯作者)，Icahn Sch Med Mt Sinai, Tisch Canc Inst, Dept Oncol Sci, New York, NY 10029 USA.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023; 145 (27): 14932

Abstract

With advances in chemically inducedproximity technologies, heterobifunctionalmodalities such as proteolysis targeting chimeras (PROTACs) have beensucc......

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