C17orf80 binds the mitochondrial genome to promote its replication

Wu, H; Zhang, WS; Xu, FL; Peng, K; Liu, XY; Ding, WQ; Ma, Q; Cheng, HP; Wang, XH

Wang, XH (通讯作者),Peking Univ, State Key Lab Membrane Biol, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med,Peking Tsinghua Ctr Life Sci,Coll Fut, Beijing, Peoples R China.;Wang, XH (通讯作者),Chinese Acad Med Sci, PKU Nanjing Inst Translat Med, Res Unit Mitochondria Brain Dis, Nanjing, Peoples R China.

JOURNAL OF CELL BIOLOGY, 2023; 222 (10):

Abstract

Wu et al. show that C17orf80 is a bona fide mitochondrial nucleoid protein, and that it acts to promote mtDNA replication. This work identifies a new ......

Full Text Link