Photomutagenicity of chlorpromazine and its N-demethylated metabolites assessed by NGS

Agundez, JAG; Garcia-Martin, E; Garcia-Lainez, G; Miranda, MA; Andreu, I

Miranda, MA; Andreu, I (corresponding author), Univ Politecn Valencia, Dept Quim, Inst Tecnol Quim, CSIC, Camino Vera S-N,Apdo 22012, Valencia 46071, Spain.; Miranda, MA; Andreu, I (corresponding author), Univ Politecn Valencia, Unidad Mixta Invest, IIS La Fe, Hosp Univ Politecn La Fe, Ave Fernando Abril Martorell 106, Valencia 46026, Spain.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

The human genome is constantly attacked by endogenous and exogenous agents (ultraviolet light, xenobiotics, reactive oxygen species), which can induce......

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