Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation

Raisner, R; Kharbanda, S; Jin, LY; Jeng, E; Chan, E; Merchant, M; Haverty, PM; Bainer, R; Cheung, T; Arnott, D; Flynn, EM; Romero, FA; Magnuson, S; Gascoigne, KE

Gascoigne, KE (reprint author), Genentech Inc, Dept Discovery Oncol, San Francisco, CA 94080 USA.

CELL REPORTS, 2018; 24 (7): 1722

Abstract

Acetylation of histone H3 at lysine 27 is a well-defined marker of enhancer activity. However, the functional impact of this modification at enhancers......

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