Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells

Onodera, A; Gonzalez-Avalos, E; Lio, CWJ; Georges, RO; Bellacosa, A; Nakayama, T; Rao, A

Rao, A (corresponding author), La Jolla Inst Immunol, Div Signaling & Gene Express, 9420 Athena Circle, La Jolla, CA 92037 USA.; Rao, A (corresponding author), Univ Calif San Diego, Dept Pharmacol, 9500 Gilman Dr, La Jolla, CA 92093 USA.; Rao, A (corresponding author), Univ Calif San Diego, Moores Canc Ctr, 9500 Gilman Dr, La Jolla, CA 92093 USA.

GENOME BIOLOGY, 2021; 22 (1):

Abstract

Background TET enzymes mediate DNA demethylation by oxidizing 5-methylcytosine (5mC) in DNA to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC),......

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