Combination of enzastaurin and ATRA exerts dose-dependent dual effects on ATRA-resistant acute promyelocytic leukemia cells

Liang, C; Ding, M; Weng, XQ; Sheng, Y; Wu, J; Li, ZY; Cai, X

Cai, X (reprint author), Shanghai Jiao Tong Univ, Sch Med, Rui Jin Hosp, Shanghai Inst Hematol, 197 Rui Jin Rd 2, Shanghai 200025, Peoples R China.; Cai, X (reprint author), Shanghai Jiao Tong Univ, Sch Med, Rui Jin Hosp, State Key Lab Med Genom, 197 Rui

AMERICAN JOURNAL OF CANCER RESEARCH, 2019; 9 (5): 906

Abstract

All-trans retinoic acid (ATRA) resistance continues to be a critical problem in acute promyelocytic leukemia (APL)-relapsed patients. In this study, a......

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