Fucoidans inhibited tau interaction and cellular uptake

Jin, WH; Lu, CH; Zhu, YA; Zhao, J; Zhang, WJ; Wang, LC; Linhardt, RJ; Wang, CY; Zhang, FM

Wang, CY; Zhang, FM (通讯作者),Rensselaer Polytech Inst, Ctr Biotechnol & Interdisciplinary Studies, Dept Chem & Biol Engn, Troy, NY 12180 USA.

CARBOHYDRATE POLYMERS, 2023; 299 ():

Abstract

Tau spreading in Alzheimer's disease is mediated by cell surface heparan sulfate (HS). As a class of sulfated polysaccharides, fucoidans might compete......

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