Defibrotide Therapy for SARS-CoV-2 ARDS

Frame, D; Scappaticci, GB; Braun, TM; Maliarik, M; Sisson, TH; Pipe, SW; Lawrence, DA; Richardson, PG; Holinstat, M; Hyzy, RC; Kaul, DR; Gregg, KS; Lama, VN; Yanik, GA

Yanik, GA (通讯作者)，Univ Michigan, Med Sch, Blood & Marrow Transplant Program, Ann Arbor, MI 48103 USA.;Yanik, GA (通讯作者)，Univ Michigan, Med Sch, Dept Internal Med, Div Pediat Hematol Oncol, Ann Arbor, MI 48103 USA.

CHEST, 2022; 162 (2): 346

Abstract

BACKGROUND: SARS-CoV-2-related ARDS is associated with endothelial dysfunction and profound dysregulation of the thrombotic-fibrinolytic pathway. Defi......

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