A Glycoconjugated SIRT2 Inhibitor with Aqueous Solubility Allows Structure-Based Design of SIRT2 Inhibitors

Hong, JY; Price, IR; Bai, JJ; Lie, HN

Lie, HN (reprint author), Cornell Univ, Dept Chem & Chem Biol, Ithaca, NY 14853 USA.; Lie, HN (reprint author), Cornell Univ, Howard Hughes Med Inst, Dept Chem & Chem Biol, Ithaca, NY 14853 USA.

ACS CHEMICAL BIOLOGY, 2019; 14 (8): 1802

Abstract

Small molecule inhibitors for SIRT2, a member of the sirtuin family of nicotinamide adenine dinucleotide-dependent protein lysine deacylases, have sho......

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