ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway

Kidger, AM; Sipthorp, J; Cook, SJ

Kidger, AM; Cook, SJ (reprint author), Babraham Inst, Signalling Programme, Babraham Res Campus, Cambridge CB22 3AT, England.

PHARMACOLOGY & THERAPEUTICS, 2018; 187 (): 45

Abstract

The RAS-regulated RAF-MEK1/2-ERK1/2 signalling pathway is de-regulated in a variety of cancers due to mutations in receptor tyrosine kinases (RTKs), n......

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