MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation

Zhou, PP; Ding, XD; Wan, XL; Liu, LL; Yuan, XJ; Zhang, W; Hui, XH; Meng, GX; Xiao, H; Li, B; Zhong, J; Hou, FJ; Deng, LW; Zhang, Y

Zhang, Y (reprint author), Univ Chinese Acad Sci, Chinese Acad Sci, Inst Pasteur Shanghai, Key Lab Mol Virol & Immunol, 320 Yueyang Rd, Shanghai 200031, Peoples R China.

NATURE COMMUNICATIONS, 2018; 9 ():

Abstract

Trithorax group protein MLL5 is an important epigenetic modifier that controls cell cycle progression, chromatin architecture maintenance, and hematop......

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