Feasibility and preclinical efficacy of CD7-unedited CD7 CAR T cells for T cell malignancies

Watanabe, N; Mo, FY; Zheng, R; Ma, R; Bray, VC; van Leeuwen, DG; Sritabal-Ramirez, J; Hu, HX; Wang, S; Mehta, B; Srinivasan, M; Scherer, LD; Zhang, HM; Thakkar, SG; Hill, LC; Heslop, HE; Cheng, CH; Brenner, MK; Mamonkin, M

Mamonkin, M (通讯作者),Baylor Coll Med, 1102 Bates Ave,Suite 1770-02, Houston, TX 77030 USA.

MOLECULAR THERAPY, 2023; 31 (1): 24

Abstract

Chimeric antigen receptor (CAR)-mediated targeting of T lineage antigens for the therapy of blood malignancies is frequently complicated by self-targe......

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