Compartmentalized biosynthesis of mycophenolic acid

Zhang, W; Du, L; Qu, ZP; Zhang, XW; Li, FW; Li, Z; Qi, FF; Wang, X; Jiang, YY; Men, P; Sun, JR; Cao, SN; Geng, C; Qi, FX; Wan, XB; Liu, CN; Li, SY

Li, SY (reprint author), Chinese Acad Sci, Shandong Prov Key Lab Synthet Biol, Chinese Acad Sci CAS Key Lab Biofuels, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Shandong, Peoples R China.; Li, SY (reprint author), Shandong Univ, State Key L

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019; 116 (27): 13305

Abstract

Mycophenolic acid (MPA) from filamentous fungi is the first natural product antibiotic to be isolated and crystallized, and a first-line immunosuppres......

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