Global fitness landscapes of the Shine-Dalgarno sequence

Kuo, ST; Jahn, RL; Cheng, YJ; Chen, YL; Lee, YJ; Hollfelder, F; Wen, JD; Chou, HHD

Chou, HHD (corresponding author), Natl Taiwan Univ, Dept Life Sci, Taipei 10617, Taiwan.; Chou, HHD (corresponding author), Acad Sinica, Genome & Syst Biol Degree Program, Taipei 10617, Taiwan.; Chou, HHD (corresponding author), Natl Taiwan Univ, Taipei 10617, Taiwan.

GENOME RESEARCH, 2020; 30 (5): 711

Abstract

Shine-Dalgarno sequences (SD) in prokaryotic mRNA facilitate protein translation by pairing with rRNA in ribosomes. Although conventionally defined as......

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