Creatine kinase B controls futile creatine cycling in thermogenic fat

Rahbani, JF; Roesler, A; Hussain, MF; Samborska, B; Dykstra, CB; Tsai, L; Jedrychowski, MP; Vergnes, L; Reue, K; Spiegelman, BM; Kazak, L

Kazak, L (corresponding author), McGill Univ, Goodman Canc Res Ctr, Montreal, PQ, Canada.; Kazak, L (corresponding author), McGill Univ, Dept Biochem, Montreal, PQ, Canada.

NATURE, 2021; 590 (7846):

Abstract

Obesity increases the risk of mortality because of metabolic sequelae such as type 2 diabetes and cardiovascular disease(1). Thermogenesis by adipocyt......

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