Application of a Volumetric Absorptive Microsampling (VAMS)-Based Method for the Determination of Paracetamol and Four of its Metabolites as a Tool for Pharmacokinetic Studies in Obese and Non-Obese Patients

Boffel, L; Delahaye, L; De Baerdemaeker, L; Stove, CP

Stove, CP (通讯作者),Univ Ghent, Fac Pharmaceut Sci, Dept Bioanal, Lab Toxicol, Ottergemsesteenweg 460, B-9000 Ghent, Belgium.

CLINICAL PHARMACOKINETICS, 2022; 61 (12): 1719

Abstract

Background The pharmacokinetic (PK) profile of a drug is influenced by several factors, which can lead to a suboptimal dosing regimen in specific pati......

Full Text Link