The CK1 alpha Activator Pyrvinium Enhances the Catalytic Efficiency (k(cat)/K-m) of CK1 alpha

Shen, C; Li, B; Astudillo, L; Deutscher, MP; Cobb, MH; Capobianco, AJ; Lee, E; Robbins, DJ

Robbins, DJ (reprint author), Univ Miami, Miller Sch Med, DeWitt Daughtry Family Dept Surg, Mol Oncol Program, Miami, FL 33136 USA.; Robbins, DJ (reprint author), Univ Miami, Miller Sch Med, Sylvester Canc Ctr, Miami, FL 33136 USA.; Robbins, DJ (reprint a

BIOCHEMISTRY, 2019; 58 (51): 5102

Abstract

The serine/threonine protein kinase casein kinase 1 alpha (CK1 alpha) functions as a negative regulator of Wnt signaling, phosphorylating beta-catenin......

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