A selective high affinity MYC-binding compound inhibits MYC: MAX interaction and MYC-dependent tumor cell proliferation

Castell, A; Yan, QZ; Fawkner, K; Hydbring, P; Zhang, F; Verschut, V; Franco, M; Zakaria, SM; Bazzar, W; Goodwin, J; Zinzalla, G; Larsson, LG

Larsson, LG (reprint author), Karolinska Inst, Dept Microbiol Tumor & Cell Biol, SE-17165 Stockholm, Sweden.

SCIENTIFIC REPORTS, 2018; 8 ():

Abstract

MYC is a key player in tumor development, but unfortunately no specific MYC-targeting drugs are clinically available. MYC is strictly dependent on het......

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