Lipophilic efficient phenylthiazoles with potent undecaprenyl pyrophosphatase inhibitory activity

Elsebaei, MM; Mohammad, H; Samir, A; Abutaleb, NS; Norvil, AB; Michie, AR; Moustafa, MM; Samy, H; Gowher, H; Seleem, MN; Mayhoub, AS

Mayhoub, AS (reprint author), Al Azhar Univ, Coll Pharm, Dept Pharmaceut Organ Chem, Cairo 11884, Asm, Egypt.; Seleem, MN (reprint author), Purdue Univ, Coll Vet Med, Dept Comparat Pathobiol, W Lafayette, IN 47907 USA.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019; 175 (): 49

Abstract

Antibiotic resistance remains a pressing medical challenge for which novel antibacterial agents are urgently needed. The phenylthiazole scaffold repre......

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