Abrogation of Marek's disease virus replication using CRISPR/Cas9

Hagag, IT; Wight, DJ; Bartsch, D; Sid, H; Jordan, I; Bertzbach, LD; Schusser, B; Kaufer, BB

Kaufer, BB (corresponding author), Free Univ Berlin, Inst Virol, Robert von Ostertag Str 7-13, D-14163 Berlin, Germany.; Schusser, B (corresponding author), Tech Univ Munich, Sch Life Sci Weihenstephan, Reprod Biotechnol, Liesel Beckmann Str 1, D-85354 Freising Weihenstephan, Germany.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

Marek's disease virus (MDV) is a highly cell-associated alphaherpesvirus that causes deadly lymphomas in chickens. While vaccination protects against ......

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