Neoantigen quality, not quantity

McGranahan, N; Swanton, C

McGranahan, N; Swanton, C (reprint author), UCL, Canc Inst, Canc Res UK Lung Canc Ctr Excellence, Paul OGorman Bldg,72 Huntley St, London WC1E 6BT, England.; McGranahan, N (reprint author), UCL, Canc Genome Evolut Res Grp, Canc Inst, Mortimer St, London W

SCIENCE TRANSLATIONAL MEDICINE, 2019; 11 (506):

Abstract

Prioritizing expressed clonal neoantigens in genes required for cancer cell survival may reduce the likelihood of resistance to neoantigen therapies.

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