Endogenous IL-10 maintains immune tolerance but IL-10 gene transfer exacerbates autoimmune cholangitis

Hsueh, YH; Chen, HW; Syu, BJ; Lin, CI; Leung, PSC; Gershwin, ME; Chuang, YH

Chuang, YH (reprint author), Natl Taiwan Univ, Coll Med, Dept Clin Lab Sci & Med Biotechnol, 1 Chang Te St, Taipei 10016, Taiwan.

JOURNAL OF AUTOIMMUNITY, 2018; 95 (): 159

Abstract

The immunomodulatory effect of IL-10 as an immunosuppressive and anti-inflammatory cytokine is well known. Taking advantage of our established mouse m......

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