A beta accumulation causes MVB enlargement and is modelled by dominant negative VPS4A

Willen, K; Edgar, JR; Hasegawa, T; Tanaka, N; Futter, CE; Gouras, GK

Gouras, GK (reprint author), Lund Univ, Dept Expt Med Sci, S-22184 Lund, Sweden.

MOLECULAR NEURODEGENERATION, 2017; 12 ( ):

Abstract

Background: Alzheimer's disease (AD)-linked beta-amyloid (A beta) accumulates in multivesicular bodies (MVBs) with the onset of AD pathogenesis. Alter......

Full Text Link