Engineered 3D Cardiac Fibrotic Tissue to Study Fibrotic Remodeling

Sadeghi, AH; Shin, SR; Deddens, JC; Fratta, G; Mandla, S; Yazdi, IK; Prakash, G; Antona, S; Demarchi, D; Buijsrogge, MP; Sluijter, JPG; Hjortnaes, J; Khademhosseini, A

Khademhosseini, A (reprint author), Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Biomat Innovat Res Ctr,Div Engn Med, 65 Landsdowne St, Cambridge, MA 02139 USA.; Khademhosseini, A (reprint author), MIT, Harvard MIT Div Hlth Sci & Technol, 65 Landsdow

ADVANCED HEALTHCARE MATERIALS, 2017; 6 (11):

Abstract

Activation of cardiac fibroblasts into myofibroblasts is considered to play an essential role in cardiac remodeling and fibrosis. A limiting factor in......

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