Role of glutamine synthetase in angiogenesis beyond glutamine synthesis

Eelen, G; Dubois, C; Cantelmo, AR; Goveia, J; Bruning, U; DeRan, M; Jarugumilli, G; van Rijssel, J; Saladino, G; Comitani, F; Zecchin, A; Rocha, S; Chen, RY; Huang, HL; Vandekeere, S; Kalucka, J; Lange, C; Morales-Rodriguez, F; Cruys, B; Treps, L; Ra

Eelen, G; Carmeliet, P (reprint author), Univ Leuven, Ctr Canc Biol, Leuven, Belgium.; Eelen, G; Li, XR; Carmeliet, P (reprint author), Sun Yat Sen Univ, Zhongshan Ophthalm Ctr, State Key Lab Ophthalmol, Guangzhou, Guangdong, Peoples R China.; Eelen, G; C

NATURE, 2018; 561 (7721): 63

Abstract

Glutamine synthetase, encoded by the gene GLUL, is an enzyme that converts glutamate and ammonia to glutamine. It is expressed by endothelial cells, b......

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