Loss of myeloid cell-specific SIRP alpha, but not CD47, attenuates inflammation and suppresses atherosclerosis

Singla, B; Lin, HP; Ahn, W; Xu, J; Ma, Q; Sghayyer, M; Dong, KZ; Cherian-Shaw, M; Zhou, JL; Huo, YQ; White, J; Csanyi, G

Csanyi, G (通讯作者)，Augusta Univ, Med Coll Georgia, Vasc Biol Ctr, 1460 Laney Walker Blvd, Augusta, GA 30912 USA.;Csanyi, G (通讯作者)，Augusta Univ, Dept Pharmacol & Toxicol, Med Coll Georgia, 1460 Laney Walker Blvd, Augusta, GA 30912 USA.

CARDIOVASCULAR RESEARCH, 2022; 118 (15): 3097

Abstract

Aims Inhibitors of the anti-phagocytic CD47-SIRP alpha immune checkpoint are currently in clinical development for a variety of haematological and sol......

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