Quantitative analysis and pharmacokinetic study of a novel diarylurea EGFR inhibitor (ZCJ14) in rat plasma using a validated LC-MS/MS method

Zuo, SJ; Cheng, XL; Liu, DZ; Peng, WY; Cao, YX; Zhang, SQ

Zhang, SQ (corresponding author), Xi An Jiao Tong Univ, Sch Basic Med Sci, Dept Pharmacol, Xian 710061, Shaanxi, Peoples R China.

ACTA PHARMACEUTICA, 2021; 71 (3): 415

Abstract

1-(4-(Pyrrolidin-1-yl-methyl)phenyl)-3-(4-((3-(trifluoromethyl) phenyl)amino)quinazolin-6-yAl)urea (ZCJ14), a novel epidermal growth factor receptor (......

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