Upregulated Expression of Heparanase and Heparanase 2 in the Brains of Alzheimer's Disease

Garcia, B; Martin, C; Garcia-Suarez, O; Muniz-Alonso, B; Ordiales, H; Fernandez-Menendez, S; Santos-Juanes, J; Lorente-Gea, L; Castanon, S; Vicente-Etxenausia, I; Batista, KMP; Ruiz-Diaz, I; Caballero-Martinez, MC; Merayo-Lloves, J; Guerra-Merino, I;

Fernandez-Vega, I (reprint author), Hosp Univ Araba Txagorritxu, Serv Anat Pathol, C Jose Atxotegui S-N, E-01009 Vitoria, Alava, Spain.

JOURNAL OF ALZHEIMERS DISEASE, 2017; 58 (1): 185

Abstract

Background: Heparan sulfate proteoglycans (HSPGs) promote amyloid-beta peptide and tau fibrillization in Alzheimer's disease (AD) and provide resistan......

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