mTORC1 inhibition attenuates necroptosis through RIP1 inhibition mediated TFEB activation

Abe, K; Yano, T; Tanno, M; Miki, T; Kuno, A; Sato, T; Kouzu, H; Nakata, K; Ohwada, W; Kimura, Y; Sugawara, H; Shibata, S; Igaki, Y; Ino, S; Miura, T

Miura, T (reprint author), Sapporo Med Univ, Dept Cardiovasc Renal & Metab Med, Sch Med, Chuo Ku, South 1,West 16, Sapporo, Hokkaido 0608543, Japan.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2019; 1865 (12):

Abstract

Accumulating evidence indicates that necroptosis contributes to cardiovascular diseases. We recently reported suppression of autophagy by necroptotic ......

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