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Epigenetic plasticity of enhancers in cancer

期刊: TRANSCRIPTION-AUSTIN, 2020; 11 (1)

Enhancers are cis-acting elements with many sites bound by transcription factors and activate transcription over long distance. Histone modifications ......

The pleiotropic roles of SPT5 in transcription

期刊: TRANSCRIPTION-AUSTIN, 2022; 13 (1-3)

Initially discovered by genetic screens in budding yeast, SPT5 and its partner SPT4 form a stable complex known as DSIF in metazoa, which plays pleiot......

Alternative polyadenylation regulation: insights from sequential polyadenylation

期刊: TRANSCRIPTION-AUSTIN, 2022; 13 (4-5)

The processing of the proximal and distal poly(A) sites in alternative polyadenylation (APA) has long been thought to independently occur on pre-mRNAs......

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