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Foxl2 is required for the initiation of the female pathway in a temperature-dependent sex determination system in Trachemys scripta

期刊: DEVELOPMENT, 2022; 149 (13)

KDM6B-mediated epigenetic modification of the testicular regulator Dmrtl has previously been identified as the primary switch of the male pathway in a......

JIF:4.841

FOXP4 differentially controls cold-induced beige adipocyte differentiation and thermogenesis

期刊: DEVELOPMENT, 2022; 149 (7)

Beige adipocytes have a discrete developmental origin and possess notable plasticity in their thermogenic capacity in response to various environmenta......

JIF:4.841

Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus

期刊: DEVELOPMENT, 2022; 149 (10)

Recent evidence has shown that presenilin enhancer 2 (Pen2; Psenen) plays an essential role in corticogenesis by regulating the switch of apical proge......

JIF:4.841

Csf1rb regulates definitive hematopoiesis in zebrafish

期刊: DEVELOPMENT, 2022; 149 (16)

In vertebrates, hematopoietic stem and progenitor cells (HSPCs) are capable of self-renewal and continuously replenishing all mature blood lineages th......

JIF:4.841

The Hox gene Antennapedia is essential for wing development in insects

期刊: DEVELOPMENT, 2022; 149 (2)

A long-standing view in the field of evo-devo is that insect forewings develop without any Hox gene input. The Hox gene Antennapedia (Antp), despite b......

JIF:4.841

LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development

期刊: DEVELOPMENT, 2022; 149 (6)

The mitochondrial matrix AAA(+) Lon protease (LONP1) degrades misfolded or unassembled proteins, which play a pivotal role in mitochondrial quality co......

JIF:4.841

Chemokine signaling synchronizes angioblast proliferation and differentiation during pharyngeal arch artery vasculogenesis

期刊: DEVELOPMENT, 2022; 149 (23)

Developmentally, the great vessels of the heart originate from the pharyngeal arch arteries (PAAs). During PAA vasculogenesis, PAA precursors undergo ......

JIF:4.841

An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea

期刊: DEVELOPMENT, 2022; 149 (3)

The tracheal epithelium is a primary target for pulmonary diseases as it provides a conduit for air flow between the environment and the lung lobes. T......

JIF:4.841

Kinesin motor KIFC1 is required for tubulin acetylation and actin-dependent spindle migration in mouse oocyte meiosis

期刊: DEVELOPMENT, 2022; 149 (5)

Mammalian oocyte maturation is a unique asymmetric division, which is mainly because of actin-based spindle migration to the cortex. In the present st......

JIF:4.841

The functional specificity of ERECTA-family receptors in Arabidopsis stomatal development is ensured by molecular chaperones in the endoplasmic reticulum

期刊: DEVELOPMENT, 2022; 149 (17)

Stomata are epidermal pores that control gas exchange between plants and the atmosphere. In Arabidopsis, the ERECTA family (ERECTAf) receptors, includ......

JIF:4.841

Dhx38 is required for the maintenance and differentiation of erythro-myeloid progenitors and hematopoietic stem cells by alternative splicing

期刊: DEVELOPMENT, 2022; 149 (17)

Mutations that occur in RNA-splicing machinery may contribute to hematopoiesis-related diseases. How splicing factor mutations perturb hematopoiesis, ......

JIF:4.841

Nrf2 dictates the neuronal survival and differentiation of embryonic zebrafish harboring compromised alanyl-tRNA synthetase

期刊: DEVELOPMENT, 2022; 149 (17)

tRNA synthetase deficiency leads to unfolded protein responses in neuronal disorders; however, its function in embryonic neurogenesis remains unclear.......

JIF:4.841

Phytochrome-interacting factors orchestrate hypocotyl adventitious root initiation in Arabidopsis

期刊: DEVELOPMENT, 2022; 149 (10)

Adventitious roots (ARs) are an important type of plant root and display high phenotypic plasticity in response to different environmental stimuli. It......

JIF:4.841

PPP4C facilitates homologous recombination DNA repair by dephosphorylating PLK1 during early embryo development

期刊: DEVELOPMENT, 2022; 149 (10)

Mammalian early embryo cells have complex DNA repair mechanisms to maintain genomic integrity, and homologous recombination (HR) plays the main role i......

JIF:4.841

Brain vascular damage-induced lymphatic ingrowth is directed by Cxcl12b/Cxcr4a

期刊: DEVELOPMENT, 2022; 149 (13)

After ischemic stroke, promotion of vascular regeneration without causing uncontrolled vessel growth appears to be the major challenge for pro-angioge......

JIF:4.841

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