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GLP-1R activation ameliorated novel-object recognition memory dysfunction via regulating hippocampal AMPK/NF-kappa B pathway in neuropathic pain mice

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2021; 182 ()

Growing evidences indicate that neuropathic pain is frequently accompanied with cognitive impairments, which aggravate the decrease in the quality of ......

Ceftriaxone regulates glutamate production and vesicular assembly in presynaptic terminals through GLT-1 in APP/PS1 mice

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2021; 183 ()

Perturbations in the glutamate-glutamine cycle and glutamate release from presynaptic terminals have been involved in the development of cognitive def......

Age-related alterations of default mode network in autobiographical memory: Recent versus remote events

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2021; 177 ()

Previous studies have shown that the vividness of autobiographical memory decreases over time, and older adults often retrieve fewer details than youn......

Early maternal deprivation impairs learning and memory and alters hippocampal gene expression in adult male rats

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2021; 183 ()

Maternal deprivation (MD) in early life severely disrupts hippocampal development, leading to persistent cognitive and behavior deficits. The current ......

Brd4 participates in epigenetic regulation of the extinction of remote auditory fear memory

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2021; 179 ()

Background: Inaccurate fear memories can be maladaptive and potentially portrait a core symptomatic dimension of fear adaptive disorders such as post-......

Unitization does not impede overall item recognition performance: Behavioral and event-related potential study

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2020; 167 ()

It is widely accepted that unitization can promote familiarity-based associative recognition, but the role of unitization in recognition of individual......

Taxonomic relations evoke more fear than thematic relations after fear conditioning: An EEG study

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2020; 167 ()

When fear is generalized, knowledge based on concepts is also retrieved. Concepts have two very different relations: thematic relations based on the c......

Stimulus modality influences the acquisition and use of the rule-based strategy and the similarity-based strategy in category learning

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2020; 168 ()

This study aimed to investigate whether stimulus modality influenced the acquisition and use of the rule-based strategy and the similarity-based strat......

Effects of circadian rhythm disorder on the hippocampus of SHR and WKY rats

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2020; 168 ()

The present study investigated the effects of circadian rhythm disorder (CRD) on the hippocampus of SHR and WKY rats. Male SHR rats (n = 27) and WKY r......

More dynamic, more quantitative, unexpectedly intricate: Advanced understanding on synaptic RNA localization in learning and memory

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2020; 168 ()

Synaptic signaling exhibits great diversity, complexity, and plasticity which necessitates maintenance and rapid modification of a local proteome. One......

Temporal dynamics of Arc/Arg3.1 expression in the dorsal striatum during acquisition and consolidation of a motor skill in mice

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2020; 168 ()

Region- and pathway-specific plasticity within striatal circuits is critically involved in the acquisition and long-term retention of a new motor skil......

Modulation of the MAPKs pathways affects A beta-induced cognitive deficits in Alzheimer's disease via activation of alpha 7nAChR

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2020; 168 ()

Cognitive impairment in Alzheimer's disease (AD) is characterized by being deficient at learning and memory. A beta(1-)(42) oligomers have been shown ......

Chronic ghrelin administration suppresses IKK/NF-kappa B/BACE1 mediated A beta production in primary neurons and improves cognitive function via upregulation of PP1 in STZ-diabetic rats

期刊: NEUROBIOLOGY OF LEARNING AND MEMORY, 2020; 169 ()

Diabetic rats display cognition impairments accompanied by activation of NF-kappa B signalling and increased A beta expression. Ghrelin has been sugge......

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