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Inflammation-responsive delivery systems for the treatment of chronic inflammatory diseases

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 2021; 11 (4)

Inflammation is the biological response of immune system to protect living organisms from injurious factors. However, excessive and uncontrolled infla......

Antimicrobial nanomedicine for ocular bacterial and fungal infection

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 2021; 11 (4)

Ocular infection induced by bacteria and fungi is a major cause of visual impairment and blindness. Topical administration of antibiotics remains the ......

Titanium dioxide nanotubes as drug carriers for infection control and osteogenesis of bone implants

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 2021; 11 (4)

Titanium implants have been widely used as one of the most effective treatments of bone defects. However, the lack of osteogenesis and bacteria-resist......

Self-luminescent photodynamic therapy and pathogen detection for infectious diseases

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 2021; 11 (4)

The importance of detection and treatments of infectious diseases has been stressed to the world by the ongoing COVID-19 pandemic. As a substitution o......

Co-delivery of doxorubicin and SIS3 by folate-targeted polymeric micelles for overcoming tumor multidrug resistance

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, ; ()

Multidrug resistance (MDR) is considered as a critical limiting factor for the successful chemotherapy, which is mainly characterized by the overexpre......

Irinotecan and berberine co-delivery liposomes showed improved efficacy and reduced intestinal toxicity compared with Onivyde for pancreatic cancer

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, ; ()

Onivyde is the first irinotecan (IRI) nanoliposome that could improve pharmacokinetics and tumor biodistribution of irinotecan. Although FDA approves ......

Influencing factors and drug application of iontophoresis in transdermal drug delivery: an overview of recent progress

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, ; ()

Transdermal drug delivery is limited by the stratum corneum of skin, which blocks most molecules, and thus, only few molecules with specific physicoch......

An overview of chitosan and its application in infectious diseases

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, ; ()

Infectious diseases, such as the coronavirus disease-19, SARS virus, Ebola virus, and AIDS, threaten the health of human beings globally. New viruses,......

Topographical nanostructures for physical sterilization

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, ; ()

The development in nanobiotechnology provides an in-depth understanding of cell-surface interactions at the nanoscale level. Particularly, several sur......

Hydroxycamptothecin (HCPT)-loaded PEGlated lipid-polymer hybrid nanoparticles for effective delivery of HCPT: QbD-based development and evaluation

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, ; ()

Lipid-polymer hybrid nanoparticles (LPNs) are promising drug delivery systems in various of disease treatment areas, particularly for cancer treatment......

Azithromycin-loaded linolenic acid-modified methoxy poly(ethylene glycol) micelles for bacterial infection treatment

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, ; ()

In the study, new polymeric micelles loaded with azithromycin were prepared to enhance azithromycin's solubility and evaluate its in vitro/in vivo ant......

Hexyl-aminolevulinate ethosome-mediated photodynamic therapy against acne: in vitro and in vivo analyses

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, ; ()

Biofilm formation by Propionibacterium acnes is known to cause failure of anti-acne treatment. Conventional therapies for acne are typically inadequat......

Ultrasound-responsive polymer-based drug delivery systems

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, ; ()

Ultrasound-responsive polymeric materials have received a tremendous amount of attention from scientists for several decades. Compared to other stimul......

The integrin facilitated internalization of fibronectin-functionalized camptothecin-loaded DNA-nanofibers for high-efficiency anticancer effects

期刊: DRUG DELIVERY AND TRANSLATIONAL RESEARCH, 2020; 10 (5)

Camptothecin (CMPT) in a flee form is extremely cytotoxic as well as hydrophobic drug, and is considered to be highly contagious for systemic administ......

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